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The hymen is a membrane of tissue that surrounds or partially covers the vaginal opening. The Cochrane Database of Systematic Reviews 7: Love, Sex and Everything in Between. The vaginal microbiota resides in and on the outermost layer of the vaginal epithelium. Vaginal evisceration is a serious complication of a vaginal hysterectomy and occurs when the vaginal cuff ruptures , allowing the small intestine to protrude from the vagina.